Document Detail


Immunopathological diagnosis of cicatricial pemphigoid with desquamative gingivitis. A case report.
MedLine Citation:
PMID:  11288799     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cicatricial pemphigoid (CP) is a chronic subepidermal bullous dermatosis which primarily involves the mucous membranes. The oral cavity and the eye are most frequently involved. Since extension of the lesion into the pharynx and esophagus causes sore throat and dysphagia and progressive ocular lesions may cause blindness, early and valid diagnosis is very important. Here we present a case of cicatricial pemphigoid with onset at age 45 in a patient who manifested severe periodontal disease and showed the lesion on the mucous membranes of the mouth (desquamative gingivitis), skin, and eyes. Since definite diagnosis is very important, we describe how we made a differential diagnosis from other diseases which also accompany desquamative gingivitis. We examined the clinical manifestations, blood test results, HLA-genotype, histopathologic findings of the affected tissue, and immunological findings in relation to autoimmunity. Since many of the CP cases are first referred to periodontists or dentists, we believe that the diagnostic strategy described in the present study will be quite informative for making rapid and definite diagnoses of similar cases.
Authors:
M Kurihara; F Nishimura; T Hashimoto; A Komai; H Ueda; S Kokeguchi; S Takashiba; Y Murayama
Related Documents :
7259249 - Verruciform xanthoma of the penis.
23554149 - Elastic fibers in elastofibroma dorsi by fine-needle aspiration.
10947249 - The prevalence of oral mucosal lesions in a population in ljubljana, slovenia.
11853309 - Presumably entomophthoramycosis in an hiv-infected patient: the first in thailand.
871619 - Recurrent massive haemorrhage from benign hepatic tumours secondary to oral contracepti...
6936689 - Candidiasis and atrophic tongue lesions.
11028819 - Intra-epidermal and intra-dermal sebocrine adenoma with cystic degeneration and hemorrh...
11893269 - Cowden's disease: a rare cause of oral papillomatosis.
16648889 - Ameloblastic carcinoma arising from anterior skull base.
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of periodontology     Volume:  72     ISSN:  0022-3492     ISO Abbreviation:  J. Periodontol.     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-04-05     Completed Date:  2001-05-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  243-9     Citation Subset:  D; IM    
Affiliation:
Department of Periodontology and Endodontology, Okayama University Dental School, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Antibodies, Bacterial / blood
Autoimmune Diseases / diagnosis
Conjunctivitis / diagnosis,  immunology
Diagnosis, Differential
Female
Fluorescent Antibody Technique, Direct
Genotype
Gingivitis / diagnosis*,  immunology
HLA Antigens / analysis,  genetics
Humans
Immunoglobulin G / blood
Middle Aged
Pemphigoid, Benign Mucous Membrane / diagnosis*,  immunology
Periodontitis / diagnosis,  immunology,  microbiology
Prevotella intermedia / immunology
Chemical
Reg. No./Substance:
0/Antibodies, Bacterial; 0/HLA Antigens; 0/Immunoglobulin G

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Periodontal regeneration of a class II furcation defect utilizing a bioabsorbable barrier in a human...
Next Document:  Guided bone regeneration for dehiscence and fenestration defects on implants using an absorbable pol...