| Immunopathogenesis of human immunodeficiency virus. | |
| | |
MedLine Citation:
|
PMID: 9692354 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Human immunodeficiency virus (HIV) types 1 and 2 infect cells of the immune system and initiate a robust immune response which counteracts the viral spread but also accelerates the destruction of the immune system. Many pathogenic mechanisms have been proposed which include viral gene products, syncytium formation, direct virus killing of cells, apoptosis, autoimmunity, cytokine and chemokine expression, superantigens, virus directed cell-mediated cytolysis, and disruption of the lymphoid architecture. At present, there is no unifying theory or experimental proof of a single or a predominant mechanism for the pathogenesis of the HIV disease. This review is intended to highlight areas of HIV research relevant to the understanding of HIV immunopathogenesis. |
| | |
Authors:
|
N Ahsan; E Langhoff |
Related Documents
:
|
8932504 - Update on the issues of hiv vaccine development. 6290954 - Addison's disease, adrenal autoantibodies and computerised adrenal tomography. 20533094 - The incidence and significance of pattern-recognition receptors in chronic viral hepati... 22930294 - High hiv vulnerability of ethnic minorities after a trans-asian highway construction in... 9802454 - Long-term effect of helicobacter pylori eradication on gastric metaplasia in patients w... 1723734 - Hepatitis c antibody testing: problems associated with non-specific binding. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Seminars in nephrology Volume: 18 ISSN: 0270-9295 ISO Abbreviation: Semin. Nephrol. Publication Date: 1998 Jul |
Date Detail:
|
Created Date: 1998-10-16 Completed Date: 1998-10-16 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8110298 Medline TA: Semin Nephrol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 422-35 Citation Subset: IM; X |
Affiliation:
|
Department of Medicine, Hershey Medical Center, Pennsylvania State University, College of Medicine, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acquired Immunodeficiency Syndrome
/
immunology Apoptosis Autoimmunity / immunology Disease Progression HIV Infections / immunology* HIV-1 / immunology* HIV-2 / immunology* Humans Lymphocyte Count Superantigens / immunology T-Lymphocytes / immunology |
| Chemical | |
Reg. No./Substance:
|
0/Superantigens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Renal pathology of human immunodeficiency virus infection.
Next Document: Pathogenesis of human immunodeficiency virus (HIV)-associated nephropathy.