Document Detail

Immunomorphological lymph node processes in some cirrhogenic liver diseases.
MedLine Citation:
PMID:  1266678     Owner:  NLM     Status:  MEDLINE    
Dynamics of the lymph node modifications as well as hepatic and immunoserological in various cirrhogenic hepatopathies have been studied on human and experimental material. Lymph nodes showed early and progressively immunomorphological reactions with maximum intensity in evolutive stages of certain cirrhoses. Such reactions as well as in other areas of reticulo-endothelial system are decreasing during the immunosuppressive treatment and in advanced stages of cirrhosis. The lymph nodes participation in the pathogenic mechanism of some cirrhogenic hepatopathies has been very little studied, whereas that of the liver and of the spleen has been more approached. Our previous investigations (1) have disclosed the existence of some chronic lymphadenites as well as reactional reticuloses on necroptic material from young cirrhotics. Equally, during some preliminary experimental studies (7) We remarked intense lymph node reactions even in incipient phases of cirrhoses, which fact stirred us up to examine them thoroughly.
M Laky; D Laky
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in experimental medicine and biology     Volume:  66     ISSN:  0065-2598     ISO Abbreviation:  Adv. Exp. Med. Biol.     Publication Date:  1976  
Date Detail:
Created Date:  1976-07-06     Completed Date:  1976-07-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0121103     Medline TA:  Adv Exp Med Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  673-8     Citation Subset:  IM    
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MeSH Terms
Bone Marrow / pathology
Cell Differentiation
Immunoglobulin G / analysis
Immunoglobulin M / analysis
Liver / pathology
Liver Cirrhosis / immunology*,  pathology
Lymph Nodes / immunology*,  pathology
Macrophages / pathology
Mice, Inbred AKR
Plasma Cells / pathology
Spleen / pathology
Reg. No./Substance:
0/Immunoglobulin G; 0/Immunoglobulin M

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