Document Detail


Immunometabolism: an emerging frontier.
MedLine Citation:
PMID:  21469396     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Immunometabolism is an emerging field of investigation at the interface between the historically distinct disciplines of immunology and metabolism. Accelerating interest in this area is being fuelled by the obesity epidemic and the relatively recent realization that obesity affects the immune system and promotes inflammation, and that obesity-induced inflammation potentially promotes a variety of chronic conditions and diseases. The multilevel interactions between the metabolic and immune systems suggest pathogenic mechanisms that may underlie many of the downstream complications of obesity and offer substantial therapeutic promise.
Authors:
Diane Mathis; Steven E Shoelson
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Publication Detail:
Type:  Introductory Journal Article    
Journal Detail:
Title:  Nature reviews. Immunology     Volume:  11     ISSN:  1474-1741     ISO Abbreviation:  Nat. Rev. Immunol.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-04-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101124169     Medline TA:  Nat Rev Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  81     Citation Subset:  IM    
Affiliation:
Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA. dm@hms.harvard.edu
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