Document Detail


Immunology of mycobacterial infections: with special reference to Mycobacterium avium subspecies paratuberculosis.
MedLine Citation:
PMID:  18656706     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The interplay between mycobacteria and host determines the outcome of infection. After uptake of mycobacteria by macrophages, several possible scenarios may emerge; mycobacteria may be destroyed immediately or there is establishment of persistent infection. This review is focused around mycobacteria-host interactions with reference to Mycobacterium avium subspecies paratuberculosis (MAP) infection and highlights protective mechanisms involved in order to design vaccines and other control strategies.
Authors:
Jagdeep Singh Sohal; S V Singh; P Tyagi; Swati Subhodh; P K Singh; A V Singh; K Narayanasamy; Neelam Sheoran; Komal Singh Sandhu
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-03-04
Journal Detail:
Title:  Immunobiology     Volume:  213     ISSN:  0171-2985     ISO Abbreviation:  Immunobiology     Publication Date:  2008  
Date Detail:
Created Date:  2008-07-28     Completed Date:  2008-10-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8002742     Medline TA:  Immunobiology     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  585-98     Citation Subset:  IM    
Affiliation:
Central Institute for Research on Goats, Makhdoom, P.O. Farah, District Mathura 281122, Uttar Pradesh, India.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antibodies, Bacterial / biosynthesis
CD4-Positive T-Lymphocytes / immunology
Cytokines / immunology,  metabolism*
Cytotoxicity, Immunologic
Dendritic Cells / immunology
Humans
Macrophages / immunology*,  microbiology
Mycobacterium avium subsp. paratuberculosis / immunology*,  pathogenicity
Paratuberculosis / immunology*,  microbiology
Phagocytosis
Receptors, Antigen, T-Cell, gamma-delta / immunology,  metabolism
Toll-Like Receptors / immunology*,  metabolism
Chemical
Reg. No./Substance:
0/Antibodies, Bacterial; 0/Cytokines; 0/Receptors, Antigen, T-Cell, gamma-delta; 0/Toll-Like Receptors

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