Document Detail

Immunology of AIDS related to psoriasis.
MedLine Citation:
PMID:  2230207     Owner:  NLM     Status:  MEDLINE    
The association of severe psoriasis with HIV infection, which dysregulates and destroys the human immune system, supports the hypothesis that psoriasis is an immunologically mediated disease. Psoriasis and Kaposi's sarcoma share angiogenesis as basic early findings and could both be caused by differential cytokine expression or responsiveness. AIDS and research models including transgenic mice offer new models in which to study the role of the immune system and specific gene products in the pathogenesis of psoriasis and other skin diseases.
M Duvic
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  The Journal of investigative dermatology     Volume:  95     ISSN:  0022-202X     ISO Abbreviation:  J. Invest. Dermatol.     Publication Date:  1990 Nov 
Date Detail:
Created Date:  1990-12-21     Completed Date:  1990-12-21     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0426720     Medline TA:  J Invest Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  38S-40S     Citation Subset:  IM; X    
Dept of Dermatology, University of TX Medical School, Houston 77030.
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MeSH Terms
Acquired Immunodeficiency Syndrome / complications,  immunology*
Opportunistic Infections / complications,  immunology*
Psoriasis / complications,  immunology*
Grant Support

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