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Immunologically based control strategies for ostertagiosis in cattle: where do we stand ?
MedLine Citation:
PMID:  21722144     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Ostertagia ostertagi is one of the most important gastrointestinal parasites infecting millions of cattle in temperate climate areas. Since infection leads to significant losses in productivity, farmers are pushed, due to the on-going intensification of the livestock production systems, to frequently administer anthelmintics in order to minimize the exposure of their animals to this parasite. However, whether such approach is sustainable in the long term, especially in an era of emerging drug resistance and global climatic changes, is still a matter of debate. Immunological control of worm infections through vaccination is often put forward as the most rational and cost-effective alternative for anthelmintics to control helminth infections. However, the development of an immunologically based control strategy requires a thorough knowledge of the host-parasite interactions, the immune responses involved and the biology of the parasite itself. The aim of this review is to consolidate information available in these areas, specifically for O. ostertagi, and identify some critical gaps in our current knowledge.
Authors:
M Rinaldi; P Geldhof
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-1
Journal Detail:
Title:  Parasite immunology     Volume:  -     ISSN:  1365-3024     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7910948     Medline TA:  Parasite Immunol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Blackwell Publishing Ltd.
Affiliation:
Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Belgium.
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