| Immunological tolerance in chickens hatching from eggs injected with cell-associated herpesvirus of Turkey (HVT). | |
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MedLine Citation:
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PMID: 12631525 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cell-associated herpesvirus of turkeys (HVT) was inoculated in ovo at various stages of incubation. Chickens hatching from these eggs were tested for anti-HVT antibodies by several serologic procedures including enzyme-linked immunosorbent assay, indirect immunofluorescence assays, and western blot. Viremic chickens that remained free of detectable antibodies were considered tolerant to HVT. Chickens exposed to HVT at embryonation day 14 or earlier had 6-33% incidence of tolerance. Tolerant chickens developed persistent HVT viremia. A preliminary challenge experiment provided circumstantial evidence that tolerant to HVT may be associated with reduced resistance to virulent Marek's disease virus. Tolerance to HVT did not influence the ability of the chickens to produce antibodies against an extraneous antigen or respond to a T cell mitogen. |
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Authors:
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Y Zhang; J M Sharma |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Developmental and comparative immunology Volume: 27 ISSN: 0145-305X ISO Abbreviation: Dev. Comp. Immunol. Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-03-12 Completed Date: 2003-11-03 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7708205 Medline TA: Dev Comp Immunol Country: United States |
Other Details:
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Languages: eng Pagination: 431-8 Citation Subset: IM |
Copyright Information:
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Copyright 2003 Elsevier Science Ltd. |
Affiliation:
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Department of Veterinary PathoBiology, College of Veterinary Medicine, University of Minnesota, 258 Veterinary Science Building, 1971 Commonwealth Avenue, St Paul, MN 55108, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antibodies, Viral / biosynthesis Brucella abortus / immunology Chick Embryo Chickens / growth & development, immunology*, virology* Herpesvirus 1, Meleagrid / immunology* Immune Tolerance* Injections Ovum / immunology, virology Vaccination |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Viral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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