Document Detail

Immunological study of vulvar lichen sclerosus: preliminary considerations.
MedLine Citation:
PMID:  8471134     Owner:  NLM     Status:  MEDLINE    
Sclero-atrophic lichen (LSA) is a dermatosis that is well defined from the clinical and histological viewpoints, but the etiology remains unknown. The main symptom is a permanent pruritus which results in a gynecological consultation. We have studied the immunological status of 48 patients with LSA and 33 controls. The LSA patients showed a significant diminution of peripheral CD3 and CD1 and tissue CD2, CD3, CD1 and CD8. There was no difference of IgG, IgM or tissue C3c, or serum C3c and C4. These patients also had a higher incidence of autoantibodies.
F Scrimin; S Rustja; O Radillo; C Volpe; U Wiesenfeld; R Pregazzi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Allergie et immunologie     Volume:  25     ISSN:  0397-9148     ISO Abbreviation:  Allerg Immunol (Paris)     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-05-20     Completed Date:  1993-05-20     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0245775     Medline TA:  Allerg Immunol (Paris)     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  22-3     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, University of Trieste, Italy.
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MeSH Terms
Aged, 80 and over
Autoantibodies / blood*
Complement System Proteins / analysis*
Immunoglobulins / blood*
Lymphocyte Subsets / pathology*
Middle Aged
Vulvar Lichen Sclerosus / immunology*,  pathology
Reg. No./Substance:
0/Autoantibodies; 0/Immunoglobulins; 9007-36-7/Complement System Proteins

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