Document Detail


Immunological studies in Bloom's syndrome. A follow-up report.
MedLine Citation:
PMID:  1809227     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Longitudinal immunological studies were performed in five patients with Bloom's syndrome. Serum IgG concentration showed no age-related increase. IgA levels were below the 10th percentile in childhood, but rose to normal in all but one. IgM was decreased in four patients at diagnosis and remained so in three of them. Cellular immunity results were very variable, even within one patient. An immunologic attrition was not demonstrated.
Authors:
C M Weemaes; J A Bakkeren; A Haraldsson; D F Smeets
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annales de génétique     Volume:  34     ISSN:  0003-3995     ISO Abbreviation:  Ann. Genet.     Publication Date:  1991  
Date Detail:
Created Date:  1992-05-21     Completed Date:  1992-05-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370562     Medline TA:  Ann Genet     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  201-5     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University Hospital, Nijmegen, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Bloom Syndrome / genetics,  immunology*
Female
Follow-Up Studies
Humans
Immunoglobulins / metabolism
Longitudinal Studies
Male
Chemical
Reg. No./Substance:
0/Immunoglobulins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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