| Immunological properties of rat phosphoglycerate mutase isozymes. | |
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MedLine Citation:
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PMID: 2844269 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In mammalian tissues three phosphoglycerate mutase (D-phosphoglycerate 2,3-phosphomutase, EC 5.4.2.1) isozymes result from the homo-dimeric and hetero-dimeric combinations of two subunits (types M and B). Whereas rabbit antisera against type M subunit (purified from rat muscle) and against type BB isozyme (purified from rat brain) possessed a high degree of specificity, both antisera reacted with type BB and MM isozymes, as demonstrated by immunoneutralization and ELISA. Both the M subunit and B subunit were more immunoreactive than their respective dimeric isozymes. Subunits type M and B may possess common antigenic determinants, and some of these determinants may be sterically hindered in their dimeric structures. |
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Authors:
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J Castellá; J Ureña; D Ludevid; J Carreras; F Climent |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biochimica et biophysica acta Volume: 956 ISSN: 0006-3002 ISO Abbreviation: Biochim. Biophys. Acta Publication Date: 1988 Sep |
Date Detail:
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Created Date: 1988-11-23 Completed Date: 1988-11-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0217513 Medline TA: Biochim Biophys Acta Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 97-102 Citation Subset: IM |
Affiliation:
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Unitat de Bioquímica, Facultat de Medicina, Universitat de Barcelona, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bisphosphoglycerate Mutase / immunology* Enzyme-Linked Immunosorbent Assay Isoenzymes / immunology* Molecular Weight Phosphotransferases / immunology* Rats |
| Chemical | |
Reg. No./Substance:
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0/Isoenzymes; EC 2.7.-/Phosphotransferases; EC 5.4.2.4/Bisphosphoglycerate Mutase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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