Document Detail

Immunological markers of Langerhans' cells in mycosis fungoides skin lesions.
MedLine Citation:
PMID:  6179366     Owner:  NLM     Status:  MEDLINE    
The patterns of two immunological markers of epidermal Langerhans' cells were compared in normal skin and mycosis fungoides (MF) skin lesions. A double-staining indirect immunofluorescence method was used. Cells suggestive of keratinocytes reacted with the anti-Ia antibodies in some cases of MF lesions, while no such pattern was seen with the thymocyte-antigen antibodies (OK T6). In other cases of MF, as in normal skin, the epidermal picture was mainly the same with the two markers. A great many of the dermal mononuclear cells in MF were reactive with the anti-Ia antibodies but only occasional dermal cells in MF and no dermal cells in normal skin stained with OK T6.
U Tjernlund
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  62     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  1982  
Date Detail:
Created Date:  1982-09-24     Completed Date:  1982-09-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  241-3     Citation Subset:  IM    
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MeSH Terms
Antibodies, Monoclonal
Histocompatibility Antigens Class II / analysis
Langerhans Cells / immunology*
Mycosis Fungoides / immunology*
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Histocompatibility Antigens Class II

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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