| Immunological aspects of epilepsy. | |
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MedLine Citation:
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PMID: 20885000 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In recent years, the concept of an immunological background of some types of epilepsy has been gaining an increasing number of supporters. The following article is an attempt to review the most significant studies that explore irregularities in patients with intractable epilepsy, search for and identify the immunological causal factors of seizures and, finally, associate these factors with particular syndromes that manifest in refractory epilepsy. We also discuss the efficacy of immunomodulatory treatment in the recognized syndromes. Last, we focus on the immunological abnormalities found in patients undergoing antiepileptic therapy with classical antiepileptic drugs as well as changes in the immune system that could be provoked by an epileptic seizure itself. |
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Authors:
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Radosław Zarczuk; Dariusz Łukasik; Marian Jedrych; Kinga K Borowicz |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Pharmacological reports : PR Volume: 62 ISSN: 1734-1140 ISO Abbreviation: Pharmacol Rep Publication Date: 2010 Jul-Aug |
Date Detail:
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Created Date: 2010-10-04 Completed Date: 2011-01-12 Revised Date: 2011-11-28 |
Medline Journal Info:
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Nlm Unique ID: 101234999 Medline TA: Pharmacol Rep Country: Poland |
Other Details:
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Languages: eng Pagination: 592-607 Citation Subset: IM |
Affiliation:
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Experimental Neuropathophysiology Unit, Department of Pathophysiology, Medical University, Jaczewskiego 8, PL 20-090 Lublin, Poland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anticonvulsants / therapeutic use* Drug Resistance Encephalitis / complications, immunology Epilepsy / drug therapy, etiology, immunology* Humans Immunologic Factors / therapeutic use* Lupus Erythematosus, Systemic / complications, immunology |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants; 0/Immunologic Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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