Document Detail

Immunologic study of antigens and molecular hybridization of nucleic acids from milk of breast cancer patients.
MedLine Citation:
PMID:  808743     Owner:  NLM     Status:  MEDLINE    
Comparative study has shown that by the gel diffusion assay both anti-HEp-2 virus serum and anti-breast cancer milk ultrasediment serum precipitated an identical antigen in human milk specimens, which was not identical with the group specific antigen of the HEp-2 virus. At the same time tha anti-breast cancer milk serum did not precipitate the HEp-2 virus. However, molecular hybridization experiments revealed nucleotide sequences homologous to nucleic acids of oncornavirus of D-type in milk obtained from breast carcinoma patients as well as in milk of healthy donors.
I N Kryukova; K V Ilyin; N N Mazurenko; L N Vasilevskaya; V M Zhdanov
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Neoplasma     Volume:  22     ISSN:  0028-2685     ISO Abbreviation:  Neoplasma     Publication Date:  1975  
Date Detail:
Created Date:  1975-12-04     Completed Date:  1975-12-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0377266     Medline TA:  Neoplasma     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  235-41     Citation Subset:  IM    
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MeSH Terms
Antigens, Neoplasm / isolation & purification
Antigens, Viral / isolation & purification
Base Sequence
Breast Neoplasms / immunology*
DNA, Neoplasm / immunology
DNA, Viral / immunology
Milk, Human / immunology*
Nucleic Acid Hybridization*
Oncogenic Viruses / immunology*
RNA, Neoplasm / immunology
Reg. No./Substance:
0/Antigens, Neoplasm; 0/Antigens, Viral; 0/DNA, Neoplasm; 0/DNA, Viral; 0/RNA, Neoplasm

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