Document Detail


Immunologic and clinical manifestations of infectious scleritis after pterygium excision.
MedLine Citation:
PMID:  17077657     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To present the immunologic status and clinical manifestations of patients who had infectious scleritis after pterygium excision. METHODS: This prospective noncomparative study of immunologic status and clinical manifestations involved 18 eyes of 18 patients with infectious scleritis (16 bacterial and 2 fungal infections) with a history of pterygium excision from 1999 to 2001. RESULTS: The period between pterygium excision and scleritis ranged from 1 to 36 years. None of the 18 patients had any history of systemic autoimmune disease. Elevated erythrocyte sedimentation rates were found in 9 (50%) of 18 patients. Elevated serum C-reactive protein levels were found in 9 (75%) of 12 patients. Other serologic tests were all negative. The most common pathogen of infectious scleritis, Pseudomonas aeruginosa, was present in 13 patients (72.2%), significantly higher than any others (P < 0.05). All of the eyeballs were salvaged, and 9 (50%) of 18 patients had final vision better than 2/20. CONCLUSION: There was no underlying autoimmune disease associated with infectious scleritis in this study. Early diagnosis and aggressive medical and surgical treatment might have saved the eyes.
Authors:
Chuan-Yi Su; Jih-Jin Tsai; Yo-Chen Chang; Chang-Ping Lin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cornea     Volume:  25     ISSN:  0277-3740     ISO Abbreviation:  Cornea     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-11-01     Completed Date:  2007-05-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8216186     Medline TA:  Cornea     Country:  United States    
Other Details:
Languages:  eng     Pagination:  663-6     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Kaohsiung Medical University, Koahsiung, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Anti-Bacterial Agents / therapeutic use
Antifungal Agents / therapeutic use
Blood Sedimentation
C-Reactive Protein / metabolism
Eye Infections, Bacterial / drug therapy,  etiology*
Eye Infections, Fungal / drug therapy,  etiology*
Female
Humans
Male
Middle Aged
Postoperative Complications*
Prospective Studies
Pseudomonas Infections / drug therapy,  etiology
Pterygium / surgery*
Scleritis / drug therapy,  immunology*,  microbiology*
Time Factors
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Antifungal Agents; 9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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