| Immunolocalization of steroidogenic enzymes in the fetal, neonatal and adult testis of the Shiba goat. | |
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MedLine Citation:
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PMID: 16365523 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The localizations of steroidogenic enzymes (P450scc, 3 beta HSD, P450c17 and P450arom) in testes of Shiba goats were investigated by immunohistochemistry. P450scc, 3 beta HSD, P450c17 and P450arom were detected in all Leydig cells of adults. P450scc and P450c17 were observed in most Leydig cells in the fetus (90 days) and neonate (15 days). 3 beta HSD and P450arom were found in some Leydig cells of the fetus with weak immunostaining but the numbers of immunopositive Leydig cells and intense immunostaining were increased in Leydig cells of the neonate. These results suggest that Shiba goat testes have the ability to synthesize progestin, androgen and estrogen in the fetus, neonate and adult, and synthesis of these steroid hormones showed an age-related rise. |
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Authors:
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Qiang Weng; Mohamed S Medan; LongQuan Ren; Gen Watanabe; Toshio Tsubota; Kazuyoshi Taya |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Experimental animals / Japanese Association for Laboratory Animal Science Volume: 54 ISSN: 1881-7122 ISO Abbreviation: Exp. Anim. Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-12-20 Completed Date: 2009-03-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9604830 Medline TA: Exp Anim Country: Japan |
Other Details:
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Languages: eng Pagination: 451-4 Citation Subset: IM |
Affiliation:
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Faculty of Biological Science and Technology, Beijing Forestry University, Beijing, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn Cytochrome P-450 Enzyme System / metabolism* Fetal Development / physiology* Fetus Fluorescent Antibody Technique, Indirect Goats / physiology* Gonadal Steroid Hormones / metabolism Immunoenzyme Techniques Leydig Cells / cytology*, enzymology Male Testis / embryology, enzymology*, growth & development |
| Chemical | |
Reg. No./Substance:
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0/Gonadal Steroid Hormones; 9035-51-2/Cytochrome P-450 Enzyme System |
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