Document Detail


Immunolocalization of nerve growth factor (NGF) and its receptors (TrkA and p75LNGFR) in the reproductive organs of Shiba goats.
MedLine Citation:
PMID:  15738622     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this study was to determine the immunolocalization of NGF and its receptors (TrkA and p75LNGFR) in the reproductive tract of the Japanese Shiba goats. Five adult goats were used in this study and sections of ovaries, uteri and oviducts were immunostained by the avidin-biotin-peroxidase complex method (ABC). The results showed that NGF and its receptors (TrkA and p75LNGFR) were expressed in granulosa cells, theca cells, interstitial cells and lutein cells in ovaries. Immunoreactions for NGF, TrkA and p75LNGFR were also detectable in epithelial cells and muscle cells of the ampulla and isthmus of the oviduct, and in epithelial cells and uterine glands of the uterus. These results strongly suggest autocrine and paracrine regulation of reproductive function by NGF in the reproductive tract of female Shiba goats.
Authors:
LongQuan Ren; Mohamed S Medan; Qiang Weng; Wanzhu Jin; ChunMei Li; Gen Watanabe; Kazuyoshi Taya
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-02-28
Journal Detail:
Title:  The Journal of reproduction and development     Volume:  51     ISSN:  0916-8818     ISO Abbreviation:  J. Reprod. Dev.     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-07-07     Completed Date:  2005-10-03     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  9438792     Medline TA:  J Reprod Dev     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  399-404     Citation Subset:  IM    
Affiliation:
Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Fallopian Tubes / chemistry,  cytology,  metabolism*
Female
Follicular Phase
Goats / anatomy & histology,  metabolism*
Immunohistochemistry
Nerve Growth Factor / analysis
Ovary / chemistry,  cytology,  metabolism*
Receptor, trkA / analysis
Receptors, Nerve Growth Factor / analysis
Uterus / chemistry,  cytology,  metabolism*
Chemical
Reg. No./Substance:
0/Receptors, Nerve Growth Factor; 9061-61-4/Nerve Growth Factor; EC 2.7.10.1/Receptor, trkA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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