Document Detail


Immunolocalization of aquaporin 1, 5, and 9 in the female pig reproductive system.
MedLine Citation:
PMID:  18824632     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thirteen mammalian aquaporin (AQP) isoforms have been identified, and they have a unique tissue-specific pattern of expression. AQPs have been documented in the reproductive system of both male and female humans, rats, and mice. However, tissue expression and cellular and subcellular localization of AQPs are unknown in the female reproductive system of pigs. In this study, AQP1 immunoreactivity was detected in the capillary endothelium of the ovary. Distinct immunolabeling of capillary endothelium was also observed in the oviduct and uterus. AQP5 was expressed in flattened follicle cells of primordial follicles, granulosa cells of developing ovarian follicles, and muscle cells of the oviduct and uterus. Staining of AQP5 was also observed in the epithelial cells of the oviduct and uterine epithelium. AQP9 immunoreactivity was observed in granulosa cells of developing follicles. AQP9 was also localized in the luminal epithelial cells of the oviduct and uterine epithelia cells. This is, to our knowledge, the first study that shows tissue expression and cellular and subcellular localization of AQPs in the reproductive system of the female pig. Moreover, these results suggest that several subtypes of the AQPs (AQP1, 5, and 9) are involved in regulation of water homeostasis in the reproductive system of gilts.
Authors:
Mariusz T Skowronski; Tae-Hwan Kwon; Søren Nielsen
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-09-29
Journal Detail:
Title:  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society     Volume:  57     ISSN:  0022-1554     ISO Abbreviation:  J. Histochem. Cytochem.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-22     Completed Date:  2009-02-13     Revised Date:  2010-09-21    
Medline Journal Info:
Nlm Unique ID:  9815334     Medline TA:  J Histochem Cytochem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  61-7     Citation Subset:  IM    
Affiliation:
Department of Animal Physiology, University of Warmia and Mazury, Oczapowskiego 1A, 10-718 Olsztyn, Poland. skowron@uwm.edu.pl
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MeSH Terms
Descriptor/Qualifier:
Animals
Aquaporin 1 / metabolism
Aquaporin 5 / metabolism
Aquaporins / metabolism*
Capillaries / metabolism
Endothelium, Vascular / metabolism
Epithelial Cells / metabolism
Fallopian Tubes / blood supply,  cytology,  metabolism*
Female
Immunoblotting
Immunohistochemistry
Myocytes, Smooth Muscle / metabolism
Ovary / blood supply,  cytology,  metabolism*
Swine / metabolism*
Uterus / blood supply,  cytology,  metabolism*
Chemical
Reg. No./Substance:
0/Aquaporin 5; 0/Aquaporins; 146410-94-8/Aquaporin 1
Comments/Corrections

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