Document Detail

Immunohistochemistry of melanocytic proliferations.
MedLine Citation:
PMID:  21732774     Owner:  NLM     Status:  In-Data-Review    
Abstract Context.-Histologic analysis allows accurate classification of most melanocytic lesions as benign or malignant. Only in a minority of lesions is it necessary to use other techniques as an aid in the diagnosis. Among them, most authors recommend immunohistochemistry. Objective.-To describe how to apply immunohistochemistry to particular differential diagnoses and the potential pitfalls. Data Sources.-Personal experience and review of literature. Conclusions.-here is no single marker, or combination thereof, that establishes an unequivocal diagnosis of melanoma or nevus. Thus it is necessary to carefully analyze the pattern of expression (patchy versus diffuse) and localization (maturation) in the context of morphologic standard features.
Victor G Prieto; Christopher R Shea
Related Documents :
11998954 - Successful management of a giant arteriovenous fistula with a combination of selective ...
16344434 - Treatment of retinal angiomatous proliferation in age-related macular degeneration: a s...
10426904 - Treatment of hyperkeratosis areolae mammae naeviformis with the carbon dioxide laser.
1054084 - Central hemangioma of the mandible: intraoral resection and reconstruction.
21357324 - Intramural esophageal bronchogenic cysts.
20224764 - Rapidly evolving giant dermatofibroma.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  135     ISSN:  1543-2165     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-07-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  853-9     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Acral junctional nevus versus acral lentiginous melanoma in situ: a differential diagnosis that shou...
Next Document:  Molecular diagnostics in melanoma: current status and perspectives.