Document Detail

Immunohistochemistry in Kaposi's sarcoma.
MedLine Citation:
PMID:  19874352     Owner:  NLM     Status:  MEDLINE    
The importance of immunohistochemistry (IHC) to our understanding, ability to confidently diagnose and treat Kaposi's sarcoma (KS) has grown steadily in the past few decades. IHC has been performed on many KS specimen types, with > 100 different primary antibodies. Therefore, it is not surprising that IHC has helped unravel the histogenesis, understand the pathogenesis and facilitate the diagnosis of KS and identify novel therapeutic targets in the disease. This paper reviews the literature on the use of IHC in the study of KS.
L Pantanowitz; C N Otis; B J Dezube
Publication Detail:
Type:  Journal Article; Review     Date:  2009-10-23
Journal Detail:
Title:  Clinical and experimental dermatology     Volume:  35     ISSN:  1365-2230     ISO Abbreviation:  Clin. Exp. Dermatol.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-23     Completed Date:  2010-05-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7606847     Medline TA:  Clin Exp Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  68-72     Citation Subset:  IM    
Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, MA, USA.
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MeSH Terms
Antibodies, Viral / metabolism
Antigens, Viral / metabolism
Cell Differentiation
Cells, Cultured
Neoplasm Staging
Sarcoma, Kaposi / genetics,  pathology*
Skin / pathology*
Skin Neoplasms / genetics,  pathology*
Reg. No./Substance:
0/Antibodies, Viral; 0/Antigens, Viral

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