Document Detail

Immunohistochemical study of fetal stem/progenitor cells from human brain transplanted into traumatized spinal cord of adult rats.
MedLine Citation:
PMID:  15452618     Owner:  NLM     Status:  MEDLINE    
Neural stem/progenitor cells from human fetal brain were grown in a tissue culture and transplanted into traumatized spinal cord of adult rats. The behavior and differentiation of transplanted cells were studied morphologically by means of histological and immunohistochemical methods and confocal microscopy. Human neural stem/progenitor cells were viable for not less than 3 months. They migrated and differentiated into neurons and glia in the traumatized spinal cord of adult rats.
O V Podgornyi; M V Marey; D O Karpenko; M A Aleksandrova; R A Poltavtseva; A V Revishchin; G A Stepanov; G T Sukhikh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  137     ISSN:  0007-4888     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-09-28     Completed Date:  2005-02-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  415-8     Citation Subset:  IM    
N. K. Koltsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow.
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MeSH Terms
Cell Differentiation / physiology
Cell Movement / physiology
Cells, Cultured
Neurons / cytology,  physiology
Rats, Wistar
Spinal Cord / cytology,  pathology*
Stem Cell Transplantation*
Stem Cells / cytology,  metabolism*
Transplantation, Heterologous*

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