Document Detail


Immunohistochemical study of 3 beta-hydroxysteroid dehydrogenase in dog's perianal sinus.
MedLine Citation:
PMID:  18637881     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study, the localization of 3 beta-hydroxysteroid dehydrogenase (3beta-HSD) activity in the wall of canine perianal sinus (PS) was determined. The 3 beta-HSD activity was found out both in the cytoplasm of cells, situated in the propria and forming clusters adjacently to apocrine glands and in the cytoplasm of some epithelial cells in apocrine cells' glands. The results obtained about the 3 beta-HSD activity allowed us to propose a role of this enzyme in PS development and possibly, in tumourogenesis.
Authors:
I Stefanov; A Vodenicharov; M Gulubova
Publication Detail:
Type:  Journal Article     Date:  2008-07-15
Journal Detail:
Title:  Anatomia, histologia, embryologia     Volume:  37     ISSN:  1439-0264     ISO Abbreviation:  Anat Histol Embryol     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-26     Completed Date:  2009-03-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7704218     Medline TA:  Anat Histol Embryol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  435-7     Citation Subset:  IM    
Affiliation:
Department of Veterinary Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, Trakia University, 6000 Stara Zagora, Bulgaria. iv_stefanov@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
3-Hydroxysteroid Dehydrogenases / metabolism*
Animals
Apocrine Glands / enzymology*,  metabolism
Dogs
Epithelial Cells / enzymology*,  metabolism
Female
Immunohistochemistry / veterinary
Male
Chemical
Reg. No./Substance:
EC 1.1.-/3-Hydroxysteroid Dehydrogenases

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