Document Detail

Immunohistochemical localization of steroidogenic enzymes in the testis of Hokkaido Sika deer (Cervus nippon yesoensis).
MedLine Citation:
PMID:  15585968     Owner:  NLM     Status:  MEDLINE    
The testes from 15 adult male Hokkaido Sika deer (Cervus nippon yesoensis) were collected during the rutting season (October and November). We investigated the localization of 4 kinds of steroidogenic enzymes (P450scc, 3betaHSD, P450c17 and P450arom) immunohistochemically in these testicular samples. The specific immunoreactivities to these enzymes were detected only in the cytoplasm of Leydig cells. This differs to the enzyme distributions reported previously in Japanese black bear, Japanese raccoon dog, Hokkaido brown bear and American black bear, in which the same immunoreactivities were detected in Leydig cells, Sertoli cells and/or spermatogenic cells. The current study suggests that in the testes of the Hokkaido Sika deer, testosterone and estradiol-17beta may be synthesized in the Leydig cells only.
Daisuke Hayakawa; Motoki Sasaki; Chihiro Akabane; Nobuo Kitamura; Toshio Tsubota; Masatsugu Suzuki; Junzo Yamada
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of veterinary medical science / the Japanese Society of Veterinary Science     Volume:  66     ISSN:  0916-7250     ISO Abbreviation:  J. Vet. Med. Sci.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-12-08     Completed Date:  2005-01-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105360     Medline TA:  J Vet Med Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1463-6     Citation Subset:  IM    
Laboratory of Anatomy, Department of Basic Veterinary Sciences, Obihiro University of Agriculture and Veterinary Medicine, Japan.
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MeSH Terms
Deer / metabolism*
Immunohistochemistry / veterinary
Steroids / biosynthesis*
Testis / enzymology*
Reg. No./Substance:

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