Document Detail

Immunohistochemical localization of polypeptide hormones in endocrine cells of the digestive tract of Branchiostoma lanceolatum.
MedLine Citation:
PMID:  7023687     Owner:  NLM     Status:  MEDLINE    
The digestive tract of the cephalochordate Branchiostoma lanceolatum was investigated with regard to occurrence and distribution of endocrine cells. By the use of the peroxidase-antiperoxidase (PAP) technique, cells in the gut epithelium reacting with antisera against 8 different mammalian polypeptide hormones were localized. Positive reactions were obtained with antisera against the four mammalian islet hormones (insulin, glucagon, pancreatic polypeptide, somatostatin) and against secretin, vasoactive intestinal polypeptide, pentagastrin and neurotensin. No immunoreactivity was found with antisera members of the lipotropin family (ACTH, met-enkephalin, alpha-endorphin), against big-gastrin, cholecystokinin, substance P and motilin. The exact mapping of the different polypeptide immunoreactive cells throughout the digestive tract of Branchiostoma lanceolatum is presented.
M Reinecke
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cell and tissue research     Volume:  219     ISSN:  0302-766X     ISO Abbreviation:  Cell Tissue Res.     Publication Date:  1981  
Date Detail:
Created Date:  1981-11-24     Completed Date:  1981-11-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0417625     Medline TA:  Cell Tissue Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  445-56     Citation Subset:  IM    
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MeSH Terms
Chordata, Nonvertebrate / analysis*,  cytology
Digestive System / analysis,  cytology
Gastrointestinal Hormones / analysis
Hormones / analysis*
Immunoenzyme Techniques
Intestinal Mucosa / analysis
Neurotensin / analysis
Pancreatic Hormones / analysis
Peptides / analysis*
Reg. No./Substance:
0/Gastrointestinal Hormones; 0/Hormones; 0/Pancreatic Hormones; 0/Peptides; 39379-15-2/Neurotensin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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