| Immunohistochemical findings in primary fallopian tube cancer. Case report. | |
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MedLine Citation:
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PMID: 20349798 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Primary fallopian tube carcinoma is a rare malignancy, representing about 1% of female genital tract malignancies. We present a case report and compare the medical performance with accessible data from the literature as well as present immunohistochemical analysis of estrogen, progesterone, and proliferative together with basic cytokeratin reactions. We found that immunohistochemical expression of ER-beta was dominant over ER-alpha which encourages further evaluations to be performed on a larger number of samples, especially taking into account the very scant progesterone receptor expression we noted. On the basis of the course of disease under study, etiological problems and the possibility of clinical misdiagnosis have been discussed. The low prevalence rate and lack of clear symptoms of this type of carcinoma makes the final clinical diagnosis almost impossible without an intraoperative histopathological study. Multicenter studies are needed to improve the understanding of possible risk factors. |
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Authors:
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G Raba; P Laudanski; L Kanczuga-Koda |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European journal of gynaecological oncology Volume: 31 ISSN: 0392-2936 ISO Abbreviation: Eur. J. Gynaecol. Oncol. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-03-30 Completed Date: 2010-04-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8100357 Medline TA: Eur J Gynaecol Oncol Country: Italy |
Other Details:
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Languages: eng Pagination: 120-2 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Provincial Hospital, Przemysl, Poland. g.raba@plusnet.pl |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Carcinoma, Papillary / chemistry*, diagnosis, pathology Estrogen Receptor alpha / analysis Estrogen Receptor beta / analysis Fallopian Tube Neoplasms / chemistry*, diagnosis, pathology Female Humans Immunohistochemistry Keratins / analysis Receptors, Progesterone / analysis |
| Chemical | |
Reg. No./Substance:
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0/Estrogen Receptor alpha; 0/Estrogen Receptor beta; 0/Receptors, Progesterone; 68238-35-7/Keratins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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