Document Detail


Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach.
MedLine Citation:
PMID:  20076883     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To determine the prevalence of Her-2/Neu-cerbb-2 in the gastric mucosa of patients with gastric adenocarcinoma in a brazilian patient group. METHODS: The immunohistochemical expression of Her-2/Neu was studied in 37 formalin-fixed paraffin-embedded tissue sections. RESULTS: The immunohistochemical reaction produced by the anti-HER-2/Neu antibody was positive in two cases (5.4%). CONCLUSION: The low prevalence of Her-2/Neu observed in these southern brazilian cases is probably due to the great number of poorly differentiated cancers in this series.
Authors:
Fernando K Cirne-Lima; Aline de Souza Rosa; Jane M U Kulczynski; Diego S Mattana; Kizzy Corezolla; Luis F Moreira
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Revista do Col?gio Brasileiro de Cirurgi?es     Volume:  36     ISSN:  1809-4546     ISO Abbreviation:  Rev Col Bras Cir     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2010-01-15     Completed Date:  2010-05-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7809515     Medline TA:  Rev Col Bras Cir     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  131-4     Citation Subset:  IM    
Affiliation:
Federal University of Rio Grande do Sul, Porto Alegre, RS, Brasil. bruce@cpovo.net
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / chemistry,  genetics*
Adult
Aged
Aged, 80 and over
Female
Humans
Immunohistochemistry
Male
Middle Aged
Receptor, erbB-2 / analysis,  biosynthesis*,  genetics*
Retrospective Studies
Stomach Neoplasms / chemistry,  genetics*
Chemical
Reg. No./Substance:
EC 2.7.10.1/Receptor, erbB-2

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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