Document Detail

Immunohistochemical distribution of MAM-3 and MAM-6 antigens in developing salivary glands of the human fetus.
MedLine Citation:
PMID:  1917564     Owner:  NLM     Status:  MEDLINE    
The immunohistochemical expression of MAM-3 and MAM-6 antigens was studied developing human fetal salivary gland removed at autopsy of 22 normal fetuses of varying maturity (10-40 weeks of gestation). The onset of functional maturation in the fetal gland was seen at 21 weeks of gestational maturity. The acini and ducts then underwent distinct alterations in antigen expression with growth and maturation until the late developmental stage (33-40 weeks of gestation) when they resemble the adult salivary gland. The role of maturing duct cells in histogenesis of salivary gland tumours is discussed.
S K Lee; C Y Lim; J G Chi; K Yamada; M Mori; A Tsubura; S Morii; J Hilgers; M Govindarajan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Histochemical journal     Volume:  23     ISSN:  0018-2214     ISO Abbreviation:  Histochem. J.     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1991-11-07     Completed Date:  1991-11-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0163161     Medline TA:  Histochem J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  355-60     Citation Subset:  IM    
Department of Oral Pathology, College of Dentistry, Seoul National University, Korea.
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MeSH Terms
Antibodies, Monoclonal
Embryonic and Fetal Development
Gene Expression
Immunohistochemistry / methods
Membrane Glycoproteins / analysis*,  immunology
Salivary Glands / chemistry,  embryology*
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Membrane Glycoproteins; 0/Mucin-1

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