Document Detail


Immunohistochemical demonstration of renin in the endometrium.
MedLine Citation:
PMID:  2679336     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Increased levels of plasma prorenin, an inactive form of renin, and renin were demonstrated during normal menstrual cycles and the source of this enzyme was thought to be the ovary. To demonstrate that endometrium may produce renin, an immunohistochemistry for human renin was used in this study. Renin containing cells either in the glands or in the stroma were demonstrated in 5 of 20 sections of endometria. Since a product of renin, angiotensin II has been found to have angiogenic properties and may have a role in repair process, we postulate that renin containing cells present only in proliferative phase endometria may be involved in repair or regeneration of the endometrium.
Authors:
G C Raju; Y S Lee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of the Academy of Medicine, Singapore     Volume:  18     ISSN:  0304-4602     ISO Abbreviation:  Ann. Acad. Med. Singap.     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-11-22     Completed Date:  1989-11-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503289     Medline TA:  Ann Acad Med Singapore     Country:  SINGAPORE    
Other Details:
Languages:  eng     Pagination:  345-7     Citation Subset:  IM    
Affiliation:
Department of Pathology, National University of Singapore.
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MeSH Terms
Descriptor/Qualifier:
Endometrium / anatomy & histology,  metabolism*
Female
Humans
Immunochemistry
Menstrual Cycle / physiology
Renin / metabolism*
Chemical
Reg. No./Substance:
EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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