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Immunohistochemical Investigation on G and D Cell Number in Antral Mucosa in patients with Helicobacter-Pylori related gastritis.
MedLine Citation:
PMID:  10993984     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
G and D cells in antral mucosa of 12 patients with clinical and morphological diagnosis of Helicobacter pylori related chronic gastritis were investigated. In all cases D cell number was significantly decreased (P < 0.05). G cell number did not show any significant difference as compared with control patients except for the cases with moderate gastric mucosal atrophy, where even G cells decreased in number. The results showed that elevated gastrin secretion as observed in H. pylori infected patients might result from reduced inhibition of G cells' secretion by D cells' producing somatostatin.
Authors:
Tzaneva
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Endocrine regulations     Volume:  29     ISSN:  1210-0668     ISO Abbreviation:  Endocr Regul     Publication Date:  1995 Dec 
Date Detail:
Created Date:  2000-09-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9112018     Medline TA:  Endocr Regul     Country:  -    
Other Details:
Languages:  ENG     Pagination:  220-224     Citation Subset:  -    
Affiliation:
Department of General and Clinical Pathology, Medical Institute, Stara Zagura, Bulgaria.
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