| Immunohistochemical Analysis of Cartilage-Derived Retinoic Acid-Sensitive Protein (CD-RAP)/Melanoma Inhibitory Activity (MIA) in Murine, Canine, Bovine, and Equine Cerebrospinal Tissues. | |
| | |
MedLine Citation:
|
PMID: 22123310 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Cartilage-derived retinoic acid-sensitive protein (CD-RAP)/Melanoma inhibitory activity (MIA), which appears abundantly in hypertrophic cartilage at the stage of endochondral ossification, is also detected in cerebrospinal fluid (CSF) following spinal cord injury. In this study, the localization of the CD-RAP/MIA molecule in the normal tissues of the spine and brain obtained from mouse, rat, dog, cattle, and horse, was examined using immunohistochemistry with a specific antibody. The positive signals of CD-RAP/MIA were found at nerve cells in the spinal cords of all species, and also especially strong at cerebellar Purkinje cells. The results suggested that CD-RAP/MIA included in normal cerebrospinal tissues could be a biomarker associated with tissue injuries, as the molecules might flow into the CSF. |
| | |
Authors:
|
Satoshi Tokunaga; Makoto Fujiki; Akira Yabuki; Kazuhiro Misumi |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-11-29 |
Journal Detail:
|
Title: The Journal of veterinary medical science / the Japanese Society of Veterinary Science Volume: - ISSN: 1347-7439 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
|
Created Date: 2011-11-29 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9105360 Medline TA: J Vet Med Sci Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Veterinary Medicine, Kagoshima University. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Quantitative Trait Loci that Control Plasma Lipid Levels in an F(2) Intercross between C57BL/6J and ...
Next Document: LINGO-2 polymorphism and the risk of Parkinson's disease in Taiwan.