| Immunoglobulin-producing tumours in dogs and cats. | |
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MedLine Citation:
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PMID: 8300910 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tumours with a plasmacytoid pattern taken from 32 dogs and four cats were examined for the presence of immunoglobulins, which would allow them to be designated as B-cell lymphomas. Within a total of 19 immunoglobulin-positive tumours, three types could be distinguished: extramedullary plasmacytoma (15), multiple myeloma (two) and immunocytoma (two). These tumours occurred in 18 of the dogs, and in one cat (extramedullary plasmacytoma). The characteristics of the immunoglobulin-producing tumours were investigated by light and electron-microscopy as well as by immunohistochemical methods. Seventeen of the 19 tumours expressed lambda-type light chains and one tumour kappa-type light chains. Heavy chains were also synthesized by five tumours. |
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Authors:
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W Breuer; F Colbatzky; S Platz; W Hermanns |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of comparative pathology Volume: 109 ISSN: 0021-9975 ISO Abbreviation: J. Comp. Pathol. Publication Date: 1993 Oct |
Date Detail:
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Created Date: 1994-03-04 Completed Date: 1994-03-04 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0102444 Medline TA: J Comp Pathol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 203-16 Citation Subset: IM |
Affiliation:
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Institute of Veterinary Pathology, University of Munich, F.R.G. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cat Diseases / metabolism*, pathology Cats Dog Diseases / metabolism*, pathology Dogs Immunoglobulin A / analysis, metabolism Immunoglobulin G / analysis, metabolism Immunoglobulin M / analysis, metabolism Immunoglobulin kappa-Chains / analysis, metabolism Immunoglobulins / analysis, metabolism* Immunohistochemistry Leukemia, Lymphocytic, Chronic, B-Cell / chemistry, metabolism, veterinary* Lymphoma, B-Cell / chemistry, metabolism, veterinary* Microscopy, Electron Multiple Myeloma / metabolism, veterinary* |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulin M; 0/Immunoglobulin kappa-Chains; 0/Immunoglobulins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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