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Immunoglobulin m nephropathy in a patient with systemic lupus.
MedLine Citation:
PMID:  22112710     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Immunoglobulin M (IgM) nephropathy is an uncommon glomerular disease characterized by IgM deposits in the mesangium. This case report describes a 52-year-old woman with a 10-year history of underlying systemic lupus erythematosus with minimal proteinuria who developed sudden onset of nephrotic syndrome. Renal biopsy revealed IgM nephropathy, with no clear evidence of lupus nephritis. Complements and dsDNA serologies were negative. The nephrotic syndrome resolved with prednisone therapy. Four months later, while receiving a maintenance dose of prednisone, the proteinuria relapsed. Remission was achieved after a repeat course of steroid therapy. Low-dose prednisone therapy was maintained thereafter for long-standing steroid-dependent lupus.
Authors:
Robert L Benz; Nancy A Finnigan; Bruce Elfenbein
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  342     ISSN:  1538-2990     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  530-2     Citation Subset:  AIM; IM    
Affiliation:
From the Department of Nephrology (rlb, naf), Lankenau Medical Center, Lankenau Institute for Medical Research, Wynnewood, Pennsylvania; Department of Pathology (be), Cooper University Hospital, Camden, New Jersey.
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