Document Detail


Immunoglobulin heavy chain patterns in reactive lymphadenopathy.
MedLine Citation:
PMID:  1918403     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thirty one lymph nodes taken from 24 benign reactive cases, three cases of angiolymphoid hyperplasia with eosinophilia, one case of Kimura's disease and three cases of Hodgkin's disease, were stained for immunoglobulin heavy chains IgG, IgM, IgA and IgE using the peroxidase-antiperoxidase method. Reticular staining of germinal centres and cells containing immunoglobulin in germinal centres and extrafollicular regions were features of all groups. No staining pattern was diagnostic for any of these conditions and in particular, the reticular staining pattern of IgE in the germinal centres that is frequently reported in Kimura's disease and in angiolymphoid hyperplasia with eosinophilia was non-specific.
Authors:
M Sundaresan; T Rhodes; A B Akosa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  44     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1991-11-07     Completed Date:  1991-11-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  753-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Histopathology, Royal Postgraduate Medical School, Hammersmith Hospital, London.
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MeSH Terms
Descriptor/Qualifier:
Angiolymphoid Hyperplasia with Eosinophilia / immunology*
Hodgkin Disease / immunology*
Humans
Immunoglobulin A / analysis
Immunoglobulin E / analysis
Immunoglobulin G / analysis
Immunoglobulin Heavy Chains / analysis*
Immunoglobulin M / analysis
Lymph Nodes / immunology
Mast Cells / immunology
Chemical
Reg. No./Substance:
0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulin Heavy Chains; 0/Immunoglobulin M; 37341-29-0/Immunoglobulin E
Comments/Corrections

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