Document Detail


Immunoglobulin-containing cells in normal human labial salivary glands.
MedLine Citation:
PMID:  4040124     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The distribution of immunoglobulin-containing cells within 8 normal human labial salivary glands was studied using an immunoperoxidase technique. Cell counts revealed that IgA-containing cells pre-dominated in all specimens and that the mean percentage class ratios for IgG:IgA:IgM:IgD cells were 4:92:3:1. IgE cells were rare and only detected in one gland. The density of IgA cells (191 cells/mm2 of labial gland section) was greater than those previously reported for the parotid and submandibular glands. These results support the view that minor salivary glands play an important role in the synthesis and secretion of salivary antibody.
Authors:
J B Matthews; A J Potts; M K Basu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International archives of allergy and applied immunology     Volume:  77     ISSN:  0020-5915     ISO Abbreviation:  Int. Arch. Allergy Appl. Immunol.     Publication Date:  1985  
Date Detail:
Created Date:  1985-08-05     Completed Date:  1985-08-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404561     Medline TA:  Int Arch Allergy Appl Immunol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  374-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Antibody-Producing Cells / cytology,  immunology*
Humans
Immunoglobulin A / metabolism
Immunoglobulins / metabolism*
Salivary Glands / immunology*
Salivary Glands, Minor / cytology,  immunology*
Chemical
Reg. No./Substance:
0/Immunoglobulin A; 0/Immunoglobulins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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