Document Detail


Immunoglobulin E in rectal mucosa of patients with proctitis.
MedLine Citation:
PMID:  53497     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rectal-biopsy specimens were obtained from a group of patients with proctitis in different stages of activity. Large numbers of brightly fluorescent IgE-producing cells were demonstrated in rectal-biopsy specimens taken from these patients during disease activity and clinical remission. An immediate hypersensitivity reaction is suggested as one of the mechanisms involved in the pathogenesis of proctitis.
Authors:
R V Heatley; B J Calcraft; R Fifield; J Rhodes; R H Whitehead; R G Newcombe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lancet     Volume:  2     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1975 Nov 
Date Detail:
Created Date:  1976-02-09     Completed Date:  1976-02-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1010-2     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Biopsy
Humans
Hypersensitivity, Immediate
Immunoglobulin A / isolation & purification
Immunoglobulin E* / isolation & purification
Immunoglobulin G / isolation & purification
Immunoglobulin M / isolation & purification
Intestinal Mucosa / immunology*
Proctitis / immunology*
Rectum / immunology*
Chemical
Reg. No./Substance:
0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulin M; 37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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