| Immunoglobulin D amyloidosis: a distinct entity. | |
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MedLine Citation:
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PMID: 22065594 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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IgD monoclonal gammopathies are uncommon. They are seen rarely as a monoclonal gammopathy of undetermined significance and are present in 1% to 2% of patients with multiple myeloma. In light chain amyloidosis, IgD monoclonal proteins are found in approximately 1% of patients. When an IgD monoclonal protein is found, amyloidosis is often omitted from the differential diagnosis. Here, we review the natural history of IgD-associated amyloidosis among 53 patients seen over 41 years. The distribution of clinical syndromes suggests that these patients have a lower frequency of renal and cardiac involvement. The overall survival of these patients does not appear to be different from that of patients who have light chain amyloidosis associated with another monoclonal protein. |
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Authors:
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Morie A Gertz; Francis K Buadi; Suzanne R Hayman; David Dingli; Angela Dispenzieri; Philip R Greipp; Shaji K Kumar; Martha Q Lacy; John A Lust; Nelson Leung; S Vincent Rajkumar; Stephen J Russell; Steven R Zeldenrust; Joseph R Mikhael; Vivek Roy; Robert A Kyle |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-7 |
Journal Detail:
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Title: Blood Volume: - ISSN: 1528-0020 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7603509 Medline TA: Blood Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Division of Hematology, Mayo Clinic, Rochester, MN, United States; |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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