| Immunogenicity of cell walls from various mycobacteria against airborne tuberculosis in mice. | |
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MedLine Citation:
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PMID: 4970218 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Protective potency of oil-treated cell walls of various mycobacteria against airborne infection of mice with a few cells of Mycobacterium tuberculosis H37Rv was compared with that of viable BCG. Although less potent than BCG cell walls, the cell walls of atypical mycobacteria of Runyon's groups I to IV protected against challenge by aerosol to some degree. Protection afforded by cell walls of H37Rv and of the avirulent mutants H37Ra and Washington II was comparable to that provided by BCG cell walls. However, cell walls of a highly virulent strain of M. bovis (Bovinus I) provided the best protection yet achieved. Present evidence suggests that protective substances are shared by all mycobacteria but in differing amounts; the relationship between virulence and immunogenicity has yet to be clarified. |
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Authors:
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W Brehmer; R L Anacker; E Ribi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of bacteriology Volume: 95 ISSN: 0021-9193 ISO Abbreviation: J. Bacteriol. Publication Date: 1968 Jun |
Date Detail:
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Created Date: 1968-10-07 Completed Date: 1968-10-07 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985120R Medline TA: J Bacteriol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2000-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals BCG Vaccine* Cell Wall / immunology Female Mice Mycobacterium / immunology*, pathogenicity Mycobacterium bovis / immunology Mycobacterium tuberculosis / immunology Tuberculosis / prevention & control Virulence |
| Chemical | |
Reg. No./Substance:
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0/BCG Vaccine |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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