Document Detail


Immunogenic and non-immunogenic hyperthyroidism. Recent trends in prealpine Switzerland and in coastal Poland.
MedLine Citation:
PMID:  7630748     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Annual occurrences of immunogenic (IH) and non-immunogenic hyperthyroidism (NIH) between Berne (1976, 1982, 1991) and Szczecin (1973, 1980, 1991) were compared. Out of 21,025 patients referred for thyroid examinations, 10.1% (average) were hyperthyroid. In Berne (former endemic goiter region) and Szczecin (without goiter endemicity) IH occurred in 41% and 68%, NIH in 59% and 32% of hyperthyroid patients, respectively. Within a stable incidence of NIH in Berne, toxic adenomas (TA) decreased from 41% (1976) to 17% (1991) (p < 0.005). In Szczecin, where iodine deficiency is in an early stage, the TA frequency did not change significantly: from 24% (1973) to 28% (1991). Increases of TA or of multifocal functional autonomy apparently "mark" incipient or, respectively, decreasing deficiencies in nutritious iodine. Hyperthyroid patients in Berne compared to Szczecin were older, both with IH (54 versus 45 y) and NIH (65 versus 52 y). Age at diagnosis was stable in Berne but increasing (p < 0.05) in Szczecin (from 43 to 52 y).
Authors:
C Als; M Listewnik; H Rösler; E Bartkowiak
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nuklearmedizin. Nuclear medicine     Volume:  34     ISSN:  0029-5566     ISO Abbreviation:  Nuklearmedizin     Publication Date:  1995 Jun 
Date Detail:
Created Date:  1995-09-07     Completed Date:  1995-09-07     Revised Date:  2007-01-12    
Medline Journal Info:
Nlm Unique ID:  7609387     Medline TA:  Nuklearmedizin     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  92-9     Citation Subset:  IM    
Affiliation:
Department of Nuclear Medicine, University of Berne, Inselspital, Switzerland.
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MeSH Terms
Descriptor/Qualifier:
Adenoma / blood,  diagnosis,  epidemiology
Adult
Age Factors
Aged
Graves Disease / blood,  diagnosis,  epidemiology*
Humans
Hyperthyroidism / blood,  diagnosis,  epidemiology*
Incidence
Middle Aged
Poland / epidemiology
Retrospective Studies
Switzerland / epidemiology
Thyroid Neoplasms / blood,  diagnosis,  epidemiology
Thyrotropin / blood
Thyrotropin-Releasing Hormone / diagnostic use
Thyroxine / blood
Triiodothyronine / blood
Chemical
Reg. No./Substance:
24305-27-9/Thyrotropin-Releasing Hormone; 6893-02-3/Triiodothyronine; 7488-70-2/Thyroxine; 9002-71-5/Thyrotropin

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