Document Detail


Immunofluorescent microscopic findings in glomerulonephritis.
MedLine Citation:
PMID:  9621476     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Histopathology and direct immunofluorescence (DIF) microscopy were performed on renal biopsy specimens of 60 clinically suspected cases of glomerulonephritis (GN). Histopathological diagnosis was obtained in 44 (73.3%) cases and immune complex deposition were detected by DIF in 28 (46.7%) cases. Immune complex deposition were observed in all cases of membranous GN, systemic lupus erythematosus (SLE), and rapidly progressive GN (RPGN), most of the cases of diffuse proliferative GN (2 out of 3) mesangioproliferative GN (12 out of 15) and focal glomeruloscleros is (3 out of 5 cases). No immune deposits were observed in minimal change GN, chronic GN, and diabetic nephropathy. Histopathological diagnosis was not obtained in 16 (26.7%) cases, 3 (5%) of which showed immune complex deposition by DIF. Anti-GBM nephritis was demonstrated in one (3.6%) case, the rest were immune complex nephritis.
Authors:
S Tabassum; K M Rahman; K Z Mamun; A N Ahmed; K M Islam; H Rahman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bangladesh Medical Research Council bulletin     Volume:  23     ISSN:  0377-9238     ISO Abbreviation:  Bangladesh Med Res Counc Bull     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-07-08     Completed Date:  1998-07-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7607686     Medline TA:  Bangladesh Med Res Counc Bull     Country:  BANGLADESH    
Other Details:
Languages:  eng     Pagination:  77-81     Citation Subset:  IM    
Affiliation:
Department of Microbiology, Institute of Postgraduate Medicine & Research, Dhaka.
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MeSH Terms
Descriptor/Qualifier:
Antigen-Antibody Complex / analysis
Basement Membrane / pathology
Biopsy, Needle
Fibrinogen / analysis
Glomerulonephritis / pathology*
Humans
Immunoglobulin A / analysis
Immunoglobulin G / analysis
Immunoglobulins / analysis
Kidney Glomerulus / pathology
Microscopy, Fluorescence
Chemical
Reg. No./Substance:
0/Antigen-Antibody Complex; 0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulins; 9001-32-5/Fibrinogen

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