| Immunofluorescence studies indicate that the basic trypsin-kallikrein-inhibitor of bovine organs (Trasylol) originates from mast cells. | |
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MedLine Citation:
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PMID: 374218 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Using the indirect immunofluorescence technique, the basic kallikrein-trypsin inhibitor of bovine organs, Trasylol, could be localized in tissue mast cells of bovine lung, liver, pancreas and parotid gland. Identification of cells exhibiting specific fluorescence as tissue mast cells was achieved by combined light and electron microscopic diagnosis of bovine liver tissue sections. The presence of Trasylol in mast cells explains the widespread distribution of this inhibitor in functionally totally different organs or tissues of the bovine organism, as determined earlier by biochemical means. Identification of Trasylol as a mast cell constituent will facilitate the search for the biological function of this inhibitory protein in connection with a unique and highly specialized cell population. |
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Authors:
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H Fritz; J Kruck; I Rüsse; H G Liebich |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hoppe-Seyler's Zeitschrift für physiologische Chemie Volume: 360 ISSN: 0018-4888 ISO Abbreviation: Hoppe-Seyler's Z. Physiol. Chem. Publication Date: 1979 Mar |
Date Detail:
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Created Date: 1979-07-16 Completed Date: 1979-07-16 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 2985060R Medline TA: Hoppe Seylers Z Physiol Chem Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 437-44 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Aprotinin / analysis* Cattle Fluorescent Antibody Technique Liver / analysis Lung / analysis Mast Cells / analysis* Pancreas / analysis Parotid Gland / analysis |
| Chemical | |
Reg. No./Substance:
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9087-70-1/Aprotinin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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