Document Detail

Immunofluorescence studies in stomach and breast carcinomas and benign breast diseases
MedLine Citation:
PMID:  6438999     Owner:  NLM     Status:  MEDLINE    
A study was made for localization of immunoglobulins and complement components in human malignant tumour tissues. There were not observed characteristical deposits on tumour cells. In a 2nd investigation where indirect immunofluorescence method was used, autologous antibodies to tumour material were not detectable. Only with anti-C3-technique, 2 sera from patients with breast cancer and 1 serum from a patient with mastopathia reacted with breast cancer tissue (allogenic system). However, a lot of autoantibodies of different specifity could be found in sera of tumour patients. The problems of unspecific staining and the occurrence of autoantibodies in tumour sera were discussed.
M Kasper
Publication Detail:
Type:  Comparative Study; English Abstract; Journal Article    
Journal Detail:
Title:  Acta histochemica     Volume:  75     ISSN:  0065-1281     ISO Abbreviation:  Acta Histochem.     Publication Date:  1984  
Date Detail:
Created Date:  1985-01-03     Completed Date:  1985-01-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370320     Medline TA:  Acta Histochem     Country:  GERMANY, EAST    
Other Details:
Languages:  ger     Pagination:  37-45     Citation Subset:  IM    
Vernacular Title:
Immunfluorescenz-Untesuchungen bei Magenund Mammakarcinomen sowie gutartigen Mammaerkrankungen.
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MeSH Terms
Antibodies, Neoplasm / analysis
Autoantibodies / analysis
Breast Diseases / immunology*
Breast Neoplasms / immunology*
Cell Nucleus / immunology
Complement Activating Enzymes / analysis
Complement C1q
Fluorescent Antibody Technique*
Immunoglobulins / analysis
Mitochondria / immunology
Muscles / immunology
Stomach Neoplasms / immunology*
Reg. No./Substance:
0/Antibodies, Neoplasm; 0/Autoantibodies; 0/Immunoglobulins; 80295-33-6/Complement C1q; EC 3.-/Complement Activating Enzymes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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