Document Detail

Immunofluorescence of the skin in allergic diseases: an investigation of patients with contact dermatitis, allergic vasculitis and atopic dermatitis.
MedLine Citation:
PMID:  76388     Owner:  NLM     Status:  MEDLINE    
Skin biopsies for immunofluorescent studies were taken from patients with contact dermatitis (positive patch tests), atopic dermatitis and allergic vasculitis for comparison with normal-appearing skin from the same patients, and from healthy controls. A variety of deposits of immunoglobulins, complement components and fibrinogen were demonstrated in 6 out of 20 patients with contact dermatitis, 7 out of 10 with atopic dermatitis, 8 out of 10 with allergic vasculitis, and in 4 out of 20 control individuals. No diagnostic pattern of deposits was found. Elevated serum IgE and eosinophilic counts were found in patients with atopic dermatitis, and high serum IgA and fibrinogen levels were found in the allergic vasculitis group.
L Secher; H Permin; F Juhl
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  58     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  1978  
Date Detail:
Created Date:  1978-05-08     Completed Date:  1978-05-08     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  117-20     Citation Subset:  IM    
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MeSH Terms
Complement System Proteins / analysis
Dermatitis, Atopic / immunology*
Dermatitis, Contact / immunology*
Fibrinogen / analysis
Fluorescent Antibody Technique
Immunoglobulins / analysis
Leukocyte Count
Middle Aged
Skin / immunology*
Vasculitis, Leukocytoclastic, Cutaneous / immunology*
Reg. No./Substance:
0/Immunoglobulins; 9001-32-5/Fibrinogen; 9007-36-7/Complement System Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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