Document Detail

Immunofluorescence microscopic studies of recurrent aphthous stomatitis.
MedLine Citation:
PMID:  7032425     Owner:  NLM     Status:  MEDLINE    
Direct immunofluorescence microscopic techniques were used to identify immunoglobulins and complement in the oral biopsy specimens of 22 patients with recurrent aphthous stomatitis (RAS). Ten (45%) of 22 patients demonstrated fluorescence along the basement membrane zone, and vascular fluorescence was seen in seven patients. These findings are in agreement with those of previous immunofluorescence microscopic studies of RAS and suggest the possibility that circulating immune complexes may play a role in the tissue damage seen in this disease.
H M VanHale; R S Rogers; J A Doyle; A L Schroeter
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of dermatology     Volume:  117     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1981 Dec 
Date Detail:
Created Date:  1982-02-22     Completed Date:  1982-02-22     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  779-81     Citation Subset:  AIM; IM    
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MeSH Terms
Antigen-Antibody Complex / analysis
Complement C3 / analysis
Fluorescent Antibody Technique
Immunoglobulins / analysis
Microscopy, Fluorescence
Middle Aged
Stomatitis, Aphthous / immunology*
Grant Support
Reg. No./Substance:
0/Antigen-Antibody Complex; 0/Complement C3; 0/Immunoglobulins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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