Document Detail


Immunodiagnosis of snake bite.
MedLine Citation:
PMID:  4216390     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Management of a patient with snake bite is influenced by the nature of the offending snake. Species diagnosis based on the patient's history and physical signs is often unreliable and the possibility of making a species diagnosis by immunological means has therefore been investigated. Wound aspirates, blister fluids, sera, and urine samples from patients with snake bite were examined for the presence of species-specific venoms using immunodiffusion. A positive species diagnosis was made in 40 out of 101 patients. Immunodiagnosis was especially successful in patients bitten by the puff adder, Bitis arietans, and the African spitting cobra, Naja nigricollis. A higher success rate could probably be achieved using more specific antisera and more sensitive assay techniques.
Authors:
B M Greenwood; D A Warrell; N M Davidson; L D Ormerod; H A Reid
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  4     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1974 Dec 
Date Detail:
Created Date:  1975-04-14     Completed Date:  1975-04-14     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  743-5     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blister
Body Fluids / analysis
Humans
Immune Sera
Immunodiffusion
Immunoelectrophoresis
Iodine Radioisotopes
Rabbits / immunology
Serologic Tests
Snake Bites / diagnosis*
Snake Venoms / analysis
Snakes
Species Specificity
Chemical
Reg. No./Substance:
0/Immune Sera; 0/Iodine Radioisotopes; 0/Snake Venoms
Comments/Corrections

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