Document Detail


Immunodiagnosis of colorectal cancer: clinical evaluation of Tennessee antigen (Tenagen).
MedLine Citation:
PMID:  6580489     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Blood samples from 172 consecutive patients undergoing complete colon investigations to exclude colorectal cancer (CC) were examined for levels of Tennessee antigen, i.e., Tenagen (Tg), and carcinoembryonic antigen. Patients included 48 with CC, 34 with adenomatous polyps, 14 with colitis, and 76 with no organic mucosal disease. All patients were investigated by the one clinical and histopathology department. Laboratory estimations were performed blindly. Although there were some statistically significant differences among average values, the degree of overlap among the groups of patients precludes the practical application of Tg in the diagnosis of CC.
Authors:
O F Dent; P H Chapuis; J E Payne; J Meyer; A M Sutherland; K J Goulston
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the National Cancer Institute     Volume:  71     ISSN:  0027-8874     ISO Abbreviation:  J. Natl. Cancer Inst.     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1984-01-07     Completed Date:  1984-01-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7503089     Medline TA:  J Natl Cancer Inst     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  893-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Antigens, Neoplasm / analysis*
Carcinoembryonic Antigen / analysis
Colitis / immunology
Colonic Diseases, Functional / immunology
Colonic Neoplasms / immunology*
False Positive Reactions
Humans
Intestinal Polyps / immunology
Middle Aged
Rectal Neoplasms / immunology*
Statistics as Topic
Chemical
Reg. No./Substance:
0/Antigens, Neoplasm; 0/Carcinoembryonic Antigen; 0/Tennessee antigen, human

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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