| Immunodiagnosis of colorectal cancer: clinical evaluation of Tennessee antigen (Tenagen). | |
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MedLine Citation:
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PMID: 6580489 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Blood samples from 172 consecutive patients undergoing complete colon investigations to exclude colorectal cancer (CC) were examined for levels of Tennessee antigen, i.e., Tenagen (Tg), and carcinoembryonic antigen. Patients included 48 with CC, 34 with adenomatous polyps, 14 with colitis, and 76 with no organic mucosal disease. All patients were investigated by the one clinical and histopathology department. Laboratory estimations were performed blindly. Although there were some statistically significant differences among average values, the degree of overlap among the groups of patients precludes the practical application of Tg in the diagnosis of CC. |
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Authors:
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O F Dent; P H Chapuis; J E Payne; J Meyer; A M Sutherland; K J Goulston |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the National Cancer Institute Volume: 71 ISSN: 0027-8874 ISO Abbreviation: J. Natl. Cancer Inst. Publication Date: 1983 Nov |
Date Detail:
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Created Date: 1984-01-07 Completed Date: 1984-01-07 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7503089 Medline TA: J Natl Cancer Inst Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 893-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antigens, Neoplasm / analysis* Carcinoembryonic Antigen / analysis Colitis / immunology Colonic Diseases, Functional / immunology Colonic Neoplasms / immunology* False Positive Reactions Humans Intestinal Polyps / immunology Middle Aged Rectal Neoplasms / immunology* Statistics as Topic |
| Chemical | |
Reg. No./Substance:
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0/Antigens, Neoplasm; 0/Carcinoembryonic Antigen; 0/Tennessee antigen, human |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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