Document Detail

Immunocytochemical localization of a substance in the eyestalk of the prawn, Palaemon serratus, reactive with an anti-FMRF-amide rabbit serum.
MedLine Citation:
PMID:  6143617     Owner:  NLM     Status:  MEDLINE    
By use of a specific antiserum against the molluscan cardio-excitatory tetrapeptide FMRF-amide in combination with the PAP-method it was possible to obtain positive immunocytochemical reactions in several neurosecretory regions of the eyestalk of the prawn Palaemon serratus. FMRF-amide-like material was found in perikarya and nerve fibers of the medulla terminalis and in neurons in the lamina ganglionaris. The immunoreactivity observed in the glandular tissue located at the basal insertion of the eyestalk muscles must be ascribed to a non-specific reaction. The identification of immunopositive nerve fibers, ending on a nerve bundle in the medulla terminalis, and the fact that immunoreactive material was absent in the neurohemal sinus gland seem to indicate a neurotransmitter/neuromodulator function.
A A Jacobs; F Van Herp
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell and tissue research     Volume:  235     ISSN:  0302-766X     ISO Abbreviation:  Cell Tissue Res.     Publication Date:  1984  
Date Detail:
Created Date:  1984-06-18     Completed Date:  1984-06-18     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0417625     Medline TA:  Cell Tissue Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  601-5     Citation Subset:  IM    
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MeSH Terms
Neurosecretory Systems / analysis*,  immunology
Neurotransmitter Agents / physiology
Oligopeptides / antagonists & inhibitors*
Palaemonidae / analysis*,  immunology
Reg. No./Substance:
0/Neurotransmitter Agents; 0/Oligopeptides; 64190-70-1/FMRFamide

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