| Immunocytochemical localization of calspectin (a non-erythroid spectrin-like protein) in thyroid glands of normal and TSH-treated rats. | |
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MedLine Citation:
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PMID: 3301749 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The localization of calspectin (fodrin, a non-erythroid spectrin-like protein), which is known to bind calmodulin and F-actin, was detected in the thyroid gland of normal and TSH-treated rats by means of light-microscopic immunocytochemistry. Calspectin was demonstrated in the cytoplasm of the follicle epithelial cells especially along the baso-lateral plasma membrane in normal rats. In TSH-treated animals, in addition to the baso-lateral plasma membrane region, the apical plasma membrane region of the follicle epithelial cells also showed positive reaction to the immunostaining. These results suggest that calspectin, in conjugation with calmodulin and actin, play a role in the secretory activities including reabsorption activity of colloid of the follicle epithelial cell. |
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Authors:
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K Ishimura; T Senda; K Kitajima; H Fujita; Y Fujio; K Sobue |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Histochemistry Volume: 86 ISSN: 0301-5564 ISO Abbreviation: Histochemistry Publication Date: 1987 |
Date Detail:
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Created Date: 1987-08-28 Completed Date: 1987-08-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0411300 Medline TA: Histochemistry Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 537-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Calmodulin-Binding Proteins / immunology, metabolism* Cell Membrane / metabolism Fluorescent Antibody Technique Histocytochemistry Male Rats Rats, Inbred Strains Thyroid Gland / drug effects, metabolism* Thyrotropin / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Calmodulin-Binding Proteins; 9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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