| Immunocytochemical localization of albumin in ovarian follicles of fertile rats. | |
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MedLine Citation:
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PMID: 3300999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to investigate whether albumin (Alb) can be detected in ovarian rat granulosa cells. Using immunocytochemistry and morphometrics, the percentages of Alb-positive follicles (follicle-index), of Alb-positive granulosa cells (granulosa-index), and of strongly reacting follicles (intensity-index) were evaluated in intact and regressing follicles of different diameter groups during different stages of the estrous cycle. In intact follicles, the follicle- and the granulosa-index increased from small-sized to large-sized follicles. Although the follicle-index did not change in any group during the stages of the estrous cycle, the granulosa-index was higher during proestrus than during the other stages. Intact follicles showed a stronger immunoreactivity than regressing follicles throughout the stages of the estrous cycle. Thus, Alb may be a requirement for the control of follicle growth in fertile rats. This Alb function may be attributable to Alb binding to specific cell-membrane components followed by the intracellular uptake of Alb-bound substances. |
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Authors:
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K Spanel-Borowski |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cell and tissue research Volume: 248 ISSN: 0302-766X ISO Abbreviation: Cell Tissue Res. Publication Date: 1987 Jun |
Date Detail:
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Created Date: 1987-08-28 Completed Date: 1987-08-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0417625 Medline TA: Cell Tissue Res Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 699-702 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Albumins
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analysis* Animals Estrus Female Fertility Granulosa Cells / cytology, physiology Immunoenzyme Techniques Ovarian Follicle / cytology*, physiology Rats Rats, Inbred Strains |
| Chemical | |
Reg. No./Substance:
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0/Albumins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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