Document Detail


Immunocytochemical investigation of ACTH-cells and vasopressin in the pituitaries of humans died from myocardial infarction.
MedLine Citation:
PMID:  3031936     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The pituitaries and adrenals of 30 patients died from extensive fresh myocardial infarction and of 25 patients died from other diseases were studied. In myocardial infarction the mean weight of the above glands was significantly higher than in other diseases. In most cases an increase in number of pituitary ACTH-cells was observed with the immunoperoxidase method. In non-cardiogenic shock (another 9 cases) gland weight was also increased but without a significant increase in the number of ACTH-cells. Hyperactivity of the anterior pituitary-adrenal system is due to a number of known factors. It may be assumed that patients who have infarction are either exposed to an extraordinary amount of stress stimuli or are more susceptible to stress than normal subjects. The findings may indicate the morphological basis of this situation. Of the shock phenomena, incomplete necrosis and haemorrhage of the adrenal cortex are frequent. In the pituitary neural lobe the neurosecretory material, which proved to be vasopressin with the PAP-method, was found to be increased more frequently in myocardial infarction than after other diseases.
Authors:
Z Zentay; D Bara; S Petri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta morphologica Hungarica     Volume:  34     ISSN:  0236-5391     ISO Abbreviation:  Acta Morphol Hung     Publication Date:  1986  
Date Detail:
Created Date:  1987-05-11     Completed Date:  1987-05-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8307964     Medline TA:  Acta Morphol Hung     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  11-21     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adrenal Cortex / pathology,  secretion
Adrenocorticotropic Hormone / analysis*
Adult
Aged
Aged, 80 and over
Female
Humans
Immunoenzyme Techniques
Male
Middle Aged
Myocardial Infarction / metabolism,  pathology*
Organ Size
Pituitary Gland, Anterior / pathology*,  secretion
Shock / metabolism,  pathology
Shock, Cardiogenic / metabolism
Vasopressins / analysis*
Chemical
Reg. No./Substance:
11000-17-2/Vasopressins; 9002-60-2/Adrenocorticotropic Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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