Document Detail

Immunocytochemical discordance in localization of pregnancy specific beta-1 glycoprotein, alpha-fetoprotein and human chorionic gonadotropin in testicular cancers.
MedLine Citation:
PMID:  6161257     Owner:  NLM     Status:  MEDLINE    
Immunocytochemical discordance of human chorionic gonadotropin, alpha-fetoprotein and pregnancy specific beta-1 glycoprotein was studied in formaldehyde-fixed tissues of 26 patients with germinal testicular cancer. The cellular localization of these 3 markers has been correlated with the serum markers in the 26 patients. Serum alpha-fetoprotein, human chorionic gonadotropin and specific beta-1 glycoprotein were elevated in 15 of 26 (58 per cent), 17 of 26 (65 per cent) and 7 of 26 (27 per cent) patients, respectively, and in 22 of 26 (85 per cent) when all markers were considered. The cellular alpha-fetoprotein was localized in 5 of 26 (19 per cent), human chorionic gonadotropin in 12 of 26 (46 per cent) and specific beta-1 glycoprotein in 9 of 26 (35 per cent) patients. When all the markers were considered 15 of 26 patients (58 per cent) had either alpha-fetoprotein, human chorionic gonadotropin or specific beta-1 glycoprotein localized in the cancer cells.
N Javadpour; M Utz; T Soares
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  124     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1980 Nov 
Date Detail:
Created Date:  1981-03-17     Completed Date:  1981-03-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  615-6     Citation Subset:  AIM; IM    
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MeSH Terms
Choriocarcinoma / analysis,  blood
Chorionic Gonadotropin / analysis*
Dysgerminoma / analysis,  blood
Immunoenzyme Techniques
Pregnancy-Specific beta 1-Glycoproteins / analysis
Teratoma / analysis,  blood
Testicular Neoplasms / analysis*,  blood
alpha-Fetoproteins / analysis*
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Pregnancy-Specific beta 1-Glycoproteins; 0/alpha-Fetoproteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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